Oral – Swallowed
Product Types: Edibles, Gummies, Capsules
Pathway: CBD is absorbed into the blood stream via your digestive tract. Once in the blood stream, it is distributed throughout the body.
Time Frame: This method of ingestion is the slowest to take effect, but is also active for longest. Peak CBD levels in your blood stream are expected anywhere between 1 – 6 hours.
Considerations: CBD ingested via this manner is first processed by the liver before passing into your bloodstream. This is called “first-pass metabolism.” For this reason, if you are on any prescription medication that is processed the same way, it could interfere with it. CBD inhibits cytochrome p450 in the same way that grapefruit does; if you currently take medication for which you’re advised not to consume grapefruit, then consider another method of ingestion such as inhalation. Also consider what food you’ve already eaten; as CBD is fat-soluble, more cannabinoids are absorbed on a full stomach.